CIALIS (Tadalafil)- How it works?

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Cialis: how it works
To understand more clearly the effect of Cialis, let’s review the biochemical mechanism of erection’s appearance. For invention of this mechanism creators of Viagra received Nobel Prize.

 

 

Briefly, the nature of biochemical mechanism of erection is as follows: nitric oxide is to be released in the tissues of penis during sexual stimulation. It causes to creation of cyclic guanosine monophosphate, this substance results to relaxation of smooth muscles of penis.
Due to action of this substance, the blood fills penis, and it causes to natural excellent erection. Besides, it will be interesting to know that nocturnal erections are not the result of erotic dreams, but are caused of relaxation of smooth muscles in penis. However, when cyclic guanosine monophosphate penetrates into blood, organism begins to secrete enzyme PDE 5 (phosphodiesterase of 5-type). This substance begins to destroy cyclic guanosine monophosphate. After the reduction of the level of cyclic guanosine monophosphate in blood, there is an outflow of blood from penis and erection disappears.

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There are two main ways to solve such a situation. The first way is a supply of nitric oxide for erection support, and the second way is the removal of PDE 5 from the blood, because this substance causes to destroying erection. At first sight, the first method is the simplest one, but it is harmful for health, because it can cause adaptation of organism and can result to reduction of nitric oxide’s natural secretion. So, normal erection may get worse.
In this case inhibition of PDE 5 secretion is more secure. But the responsibility for an erection lies only on the man who took the medicine, but it does not depend on the preparation. Cialis is a strong inhibitor of PDE 5 and its effectiveness is useless without natural sexual stimulation.
Cialis is widely used by millions of men, who have problems with various kinds of erectile dysfunction. The main substance of preparation is tadalafil.

It is strictly prohibited to use Cialis with other sexual stimulants of the same category (for example, with Viagra). This may cause to the changes of blood pressure, which result to serious problems. Combination Cialis with other sexual stimulants may result to cardiovascular complications. Therefore, before buying and taking Cialis you should consult your doctor. You need also to pay attention that taking Cialis and medicines that influence on blood pressure is strictly forbidden.

If during sexual intercourse you feel the pain in the area of chest, dizziness or nausea, you should immediately stop it and visit a doctor to have a medical care. After taking one pill of Cialis or Viagra, active ingredients of these preparations, including tadalafil, remain in organism during two days. The main side effects are headache, back pain, upset stomach, muscle aches and irritation of the nasopharynx.

The duration of above mentioned side effects last no more than some hours, but muscle pain and back pain disappear in two days. You should avoid using Cialis, if you have any serious problems with liver or kidneys. Cialis is not recommended to be used with Viagra or other strong sexual stimulants for treating ED. Mixing Cialis with alcohol beverages may increase the level of side effects. So, as in the situation with other medicines, before using Cialis, do not be lazy to consult your doctor to avoid negative consequences.

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